You have the opportunity to make a massive production line with these characters and be like yours truly.
Here's the lineup I use:
1 x Blacksmith
1 x Tailor
1 x Scribe
1 x Jewelcrafter
2 x Leatherworker
4 x Enchanter
6 x Alchemist
2 x Engineer
You will need the ability to easily farm SoH among the BS and LW. Leatherworking is one of the most desired professions simply for the leg enchants making it a consistent money maker. Blacksmithing, same deal. I used my SoH to craft epics since the most important classes in the game require them to tank, dps, or heal.
Get all of the recipes, I completed this finally. I am capable of constantly offering everything in the game on the AH and it's all profitable here. Check your server for variance.
Tailors are important because the CD is so ridiculously easy, camp V4W and make a cloth daily. Grind GL to make the epics and leg enchants. I clean up with this.
Engineering - Scopes are really good sellers, although they vary in price. Set appropriate thresholds and buy out when appropriate. People with Engineers tend to be rather lazy since they also PvP on the character (Yeah, I said it, those that PvP are usually lazy, lazy, lazy and among the laziest in the game when it comes to actually farming the SoH to make them). You also have pets.
Alchs and Enchanters should go without saying. I like being able to make high value items every day.